Hemoglobin A1C as an indicator of the accuracy of blood glucose measurement: comparative study of three technologies used for blood glucose measurements
AbstractIn previous studies, the accuracy of glucose measurements were found with significant variations in different self-monitoring devices. This study suggests Hemoglobin a1c (Hba1c) to be used as as an indicator for the accuracy of blood-glucose monitoring devices. In this study, the association between the readings of glycohematoglobin HbA1C and the hyperglycemic readings of thirty hyperglycemic patients is used as an indicator of the accuracy of three types of glucometer devices. The association between hyperglycemic readings and the percentage of HbA1C for the same patients was investigated. The results showed significant association between levels of blood glucose and the percentage of HbA1C in three devices with statistically significant ( p < 0.05). Such relationship is suggested to be used as a relative accuracy of various types of blood glucose self-monitoring devices.
 American Diabetes Association. Standards of medical care in diabetes—2006 [published correction ap-pears in Diabetes Care. 2006;29:1192], (Mayo Clin Proc. 2007;82(2):229-236
 George Dailey, Assessing Glycemic Control With Self-monitoring of Blood Glucose and Hemoglobin A1c Measurements GEORGE DAILEY, MD ). Diabetes Care. 2006;29(suppl 1):S4-S42.8.
 Cowie, C.C.; Rust, K.F.; Byrd-Holt, D.D.; Gregg, E.W.; Ford, E.S.; Geiss, L.S.; Bainbridge, K.E.; Fradkin, J.E. Prevalence of diabetes and high risk for diabetes using hemoglobin A1c criteria in the U.S. population in 1988–2006. Diabetes Care 2010, 33, 562–568.
 Narayan, K.M.; Boyle, J.P.; Geiss, L.S.; Saaddine, J.B.; Thompson, T.J. Impact of recent increase in incidence on future diabetes burden: U.S., 2005–2050. Diabetes Care 2006, 29, 2114–2116. Wild, S.; Roglic, G.; Green, A.; Sicree, R.; King, H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27, 1047–1053.
 Shaw, J.E.; Sicree, R.A.; Zimmet, P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res. Clin. Pract 2010, 87, 4–14.
 Wild, S.; Roglic, G.; Green, A.; Sicree, R.; King, H. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004, 27, 1047–1053.
 American Diabetes Association. Diagnosis and classification of diabetes mellitus. Diabetes Care 2010, 33, S62–69
 Poolsup, N.; Suksomboon, N.; Rattanasookchit, S. Meta-analysis of the benefits of self-monitoring of blood glucose on glycemic control in type 2 diabetes patients: an update. Diabetes Technol. Ther 2009, 11, 775–784.
 Murata, G.H.; Shah, J.H.; Hoffman, R.M.; Wendel, C.S.; Adam, K.D.; Solvas, P.A.; Bokhari, S.U.; Duckworth, W.C. Intensified blood glucose monitoring improves glycemic control in stable, insulin-treated veterans with type 2 diabetes: the Diabetes Outcomes in Veterans Study (DOVES). Diabetes Care 2003, 26, 1759–1763.
 Skeie, S.; Kristensen, G.B.; Carlsen, S.; Sandberg, S. Self-Monitoring of Blood Glucose in Type 1 Diabetes Patients with Insufficient Metabolic Control: Focused Self-Monitoring of Blood Glucose Intervention Can Lower Glycated Hemoglobin A1C. J. Diabetes Sci. Technol 2009, 3, 83–88.
 Tunis, S.L.; Minshall, M.E. Self-monitoring of blood glucose (SMBG) for type 2 diabetes patients treated with oral anti-diabetes drugs and with a recent history of monitoring: cost-effectiveness in the US. Curr. Med. Res. Opin 2010, 26, 151–162.
 Boutati, E.I.; Raptis, S.A. Self-monitoring of blood glucose as part of the integral care of type 2 diabetes. Diabetes Care 2009, 32(Suppl. 2), S205–210.
 Jovanovic, L.G. Using meal-based self-monitoring of blood glucose as a tool to improve outcomes in pregnancy complicated by diabetes. Endocr. Pract 2008, 14, 239–247.
 O’Kane, M.J.; Pickup, J. Self-monitoring of blood glucose in diabetes: is it worth it? Ann. Clin. Biochem 2009, 46, 273–282.
 W. L. Clarke, "Evaluating clinical accuracy of systems for self-monitoring of blood glucose." Diabetes care 10.5 (1987): 622-628.
 G. Freckmann, et al. "System accuracy evaluation of 43 blood glucose monitoring systems for self-monitoring of blood glucose according to DIN EN ISO 15197." J Diabetes Sci Technol. 6.5 (2012): 1060-1075.
 Hassan Almarshad, “Evaluation of Five Systems and Two Methods for Invasive and Minimally Invasive Blood Glucose Measurements” , Proceedings of the 36th International Conference of the IEEE Engineering in Medicine and Biology Society. (2014).
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