JOURNAL OF ADVANCES IN CHEMISTRY Interested in submitting to this journal? We recommend that you review the About the Journal page for the journal's section policies, as well as the Author Guidelines. Authors need to register with the journal prior to submitting or, if already registered, can simply log in and begin the five-step process. CIRWORLD en-US JOURNAL OF ADVANCES IN CHEMISTRY 2321-807X <p>Authors retain the copyright of their manuscripts, and all Open Access articles are distributed under the terms of the&nbsp;<a href="">Creative Commons Attribution License</a>, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.</p> <p>The use of general descriptive names, trade names, trademarks, and so forth in this publication, even if not specifically identified, does not imply that these names are not protected by the relevant laws and regulations. The submitting author is responsible for securing any permissions needed for the reuse of copyrighted materials included in the manuscript.</p> <p>While the advice and information in this journal are believed to be true and accurate on the date of its going to press, neither the authors, the editors, nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein.</p> Optimization of 6-Gingerol Extraction Assisted by Microwave From Fresh Ginger Using Response Surface Methodology <p>The present study investigates optimum conditions for Microwave assisted extraction (MAE) of 6-gingerol. Ginger was dried using a cross flow dryer at 55 ± 2 <sup>0</sup>C for eight hours. Ginger powder was extracted at three different watts (400 W, 500 W, and 600 W), temperatures (50 <sup>0</sup>C, 60 <sup>0</sup>C, 70 <sup>0</sup>C) and time (10, 20, 30 min) for optimum yield.&nbsp; 6-gingerol content was found to be 21.15 ± 0.13 and 18.81 ± 0.15 mg/g in fresh ginger and dried ginger, respectively.&nbsp; Optimized condition obtained by RSM for 6-gingerol was 400 W, 70 <sup>0</sup>C at 10 min extraction time.&nbsp; The results of MAE are expressed by 2-D contour plot and response surface curve by keeping one variable constant which showed highest yield at 600 W, 70 <sup>0</sup>C for 30 min extraction time.&nbsp; Microwave assisted extracts exhibited higher antioxidant activity in comparison with conventional extracts.</p> Vedashree M Madeneni Madhava Naidu ##submission.copyrightStatement## 2018-05-30 2018-05-30 15 2 6173 6185 10.24297/jac.v15i2.7357