https://cirworld.com/index.php/jac/issue/feed JOURNAL OF ADVANCES IN CHEMISTRY 2019-05-02T06:23:45+00:00 Gurpal Kaur editor@cirworld.com Open Journal Systems Interested in submitting to this journal? We recommend that you review the About the Journal page for the journal's section policies, as well as the Author Guidelines. Authors need to register with the journal prior to submitting or, if already registered, can simply log in and begin the five-step process. https://cirworld.com/index.php/jac/article/view/8030 Synthesis, Spectroscopic Characterization And Antimicrobial Evaluation of Novel Nitrogen Containing Metal Complexes 2019-02-22T11:18:48+00:00 Hanaa A. El-Boraey helboraey@yahoo.com Aballah El-domiaty eldomiaty_777@yahoo.com <p>Four novel Mn(II), Co(II), Cu(II) complexes with nitrogen containing ligand (L) i.e. N,N-((Z)-ethane-1,2-diylidine)bis(2-amino benzo hydrazide) have been synthesized and structurally characterized by elemental analysis, spectral, thermal (TG/DTG), molar conductance and magnetic susceptibility measurements. From the spectroscopic and magnetic studies it has been concluded that all complexes have a six coordinated octahedral geometry. The Schiff base and their metal complexes have also been screened for their antibacterial and antifungal activities by using a modified Kirby-Bauer disc diffusion method.</p> 2019-01-31T04:12:25+00:00 ##submission.copyrightStatement## https://cirworld.com/index.php/jac/article/view/8099 Structural And Vibrational Studies on Isomers of Antiviral Ribavirin Drug in Gas and Aqueous Environmental by Using The SQM Approach 2019-02-22T11:18:48+00:00 María Florencia Ladetto mflo94@yahoo.com.ar María Jimena Márquez wime.02@gmail.com Davide Romani dromaniti@gmail.com Silvia Antonia Brandán brandansa@yahoo.com.ar <p>Five stable isomers of antiviral ribavirin agent were theoretically determined in gas and aqueous solution by using the hybrid B3LYP/6-31G* method. Here, the solvent effects were studied with the self consistent reaction field (SCRF) methodology employing the polarized continuum (PCM) and the universal solvation model (SM). Structural, electronic and topological properties were reported for all isomers while the vibrational analyses were performed only for those two polymorphic structures experimentally observed in the solid phase by X-ray diffraction. Calculations have evidenced that C2 correspond to the polymorphic V1 structure while C5 to the polymorphic V2 structure. The high dipole moment values predicted for C2 and C5 in both media could probably explain their presences in the solid. Experimental available IR and Raman spectra of ribavirin in the solid state and normal internal coordinates were employed together with the scaled quantum mechanical force field (SQMFF) approach to perform the complete vibrational assignments in both media. Here, the 81 vibration modes expected for C2 and C5 in both media were completely assigned. The frontier orbitals studies reveal that C5 is the less reactive in both media. Here, the gap value observed for C5 is in agreement with the value recently reported for ribavirin by using B3LYP/6-311++G** calculations.</p> 2019-01-31T04:14:55+00:00 ##submission.copyrightStatement## https://cirworld.com/index.php/jac/article/view/8248 Oxidative Study of Benzaldehyde by Isoqauinolinium Bromo Chromate 2019-05-02T06:23:45+00:00 Arun Kumar Dwivedi drarvinddwivedi1984@gmail.com K. N. Sharma drarvinddwivedi1984@gmail.com Arvind Prasad Dwivedi adarvindchitrakoot@gmail.com <p>The kinetics analysis of the oxidative reaction between benzaldehyde and oxidant is quinolinium Bromo chromate was reported in aqueous 40% acetic acid medium at 313 K. The rate of reaction varies first-power of [IQBC] and [H<sub>2</sub>SO<sub>4</sub>], whereas fractional-order kinetics was observed for benzaldehyde. The rate constant gradually increases with decrease in dielectric constant of the medium. The neutral salt does not alter the rate. The metal cations (Cu<sup>++</sup>) slightly accelerate the rate of oxidation when added to reaction mixture. The study rules out the participation of keto form of substrate in complex formation. Benzoic acid was identified as the end-product in stoichiometrically 1:1 based mechanism. The rate law was derived in accordance with the kinetic results.</p> 2019-04-30T06:57:35+00:00 ##submission.copyrightStatement## https://cirworld.com/index.php/jac/article/view/8264 Synthesis, Spectral Characterization, Thermal and In vitro Antimicrobial Studies for Novel Co(II) and Ni(II) Complexes of (N,N'-(1,2-Phenylene)Bis(2-Aminobenzamide). 2019-05-01T08:10:21+00:00 Hanaa A. El-Boraey helboraey@yahoo.com Azza A. Serag El-Din azzatarek1965@hotmail.com Ahmed A. Sakr a_sakr210@yahoo.com <p>Novel metal complexes of Co(II) and Ni(II) have been&nbsp; prepared from reaction of their different salts with previously prepared ligand <strong>(L)</strong> namely (N,N'-(1,2-phenylene)bis(2-aminobenzamide). Synthesis ligand and its metal (II) complexes (<strong>1-5</strong>) were reported and characterized with the help of analytical and physiochemical analysis as elemental, IR spectra, thermal (TG/DTG), UV-Vis, magnetic susceptibility and molar conductance in DMF, On the view of the previous data and measurements, the structure and composition species behave as mononuclear and octahedral geometry has been proposed for all the complexes except for complex<strong> (1)</strong> adopted tetrahedral structure. Furthermore, the in vitro antibacterial Staphylococcus aureus (ATCC 25923) as Gram-positive strain, Escherichia coli (ATCC 25922) as Gram-negative strain and antifungal Candida albicans (ATCC 10231) have been studied for all samples using disc diffusion method against Ampicillin and Fluconazole as positive controls, respectively. The results show that complexation facilitates the activity of most studied metal complexes than the free ligand.</p> 2019-04-30T07:02:05+00:00 ##submission.copyrightStatement##