Synthesis, Spectral Characterization, Thermal and In vitro Antimicrobial Studies for Novel Co(II) and Ni(II) Complexes of (N,N'-(1,2-Phenylene)Bis(2-Aminobenzamide).
Novel metal complexes of Co(II) and Ni(II) have been prepared from reaction of their different salts with previously prepared ligand (L) namely (N,N'-(1,2-phenylene)bis(2-aminobenzamide). Synthesis ligand and its metal (II) complexes (1-5) were reported and characterized with the help of analytical and physiochemical analysis as elemental, IR spectra, thermal (TG/DTG), UV-Vis, magnetic susceptibility and molar conductance in DMF, On the view of the previous data and measurements, the structure and composition species behave as mononuclear and octahedral geometry has been proposed for all the complexes except for complex (1) adopted tetrahedral structure. Furthermore, the in vitro antibacterial Staphylococcus aureus (ATCC 25923) as Gram-positive strain, Escherichia coli (ATCC 25922) as Gram-negative strain and antifungal Candida albicans (ATCC 10231) have been studied for all samples using disc diffusion method against Ampicillin and Fluconazole as positive controls, respectively. The results show that complexation facilitates the activity of most studied metal complexes than the free ligand.
Ebner, T., O. Shebl, R.B. Mayer, M. Moser, W. Costamoling, and P. Oppelt, Healthy live birth using theophylline in a case of retrograde ejaculation and absolute asthenozoospermia. Fertility and sterility, 2014. 101(2): p. 340-343.
Shebl, M., S.M. Khalil, and F.S. Al-Gohani, Preparation, spectral characterization and antimicrobial activity of binary and ternary Fe (III), Co (II), Ni (II), Cu (II), Zn (II), Ce (III) and UO2 (VI) complexes of a thiocarbohydrazone ligand. Journal of Molecular Structure, 2010. 980(1-3): p. 78-87.
Swamy, S.J., S. Jyothi, P. Someshwar, K. Shashank, and G.R. Rao, Synthesis and Structural analysis of N4-donar ligands and their complexes with some bivalent transition metal ions. Journal of Applicable Chemistry, 2012. 1(2): p. 218-231.
Fache, F., E. Schulz, M.L. Tommasino, and M. Lemaire, Nitrogen-containing ligands for asymmetric homogeneous and heterogeneous catalysis. Chemical Reviews, 2000. 100(6): p. 2159-2232.
Alcón, M., M. Iglesias, and F. Sánchez, Copper and manganese complexes with C 2-multitopic ligands. X-ray crystal structure of [Cu (N, N?-bis [(S)-prolyl] phenylenediamine) H 2 O]. Catalytic properties. Inorganica chimica acta, 2002. 333(1): p. 83-92.
El-Boraey, H.A., Coordination behavior of tetraaza [N4] ligand towards Co (II), Ni (II), Cu (II), Cu (I) and Pd (II) complexes: synthesis, spectroscopic characterization and anticancer activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2012. 97: p. 255-262.
Tyagi, P., S. Chandra, B. Saraswat, and D. Sharma, Design, spectral characterization, DFT and biological studies of transition metal complexes of Schiff base derived from 2-aminobenzamide, pyrrole and furan aldehyde. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015. 143: p. 1-11.
Tyagi, P., S. Chandra, and B. Saraswat, Ni (II) and Zn (II) complexes of 2-((thiophen-2-ylmethylene) amino) benzamide: Synthesis, spectroscopic characterization, thermal, DFT and anticancer activities. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015. 134: p. 200-209.
Dharmaraja, J., P. Subbaraj, T. Esakkidurai, and S. Shobana, Coordination behavior and bio-potent aspects of Ni (II) with 2-aminobenzamide and some amino acid mixed ligands–Part II: Synthesis, spectral, morphological, pharmacological and DNA interaction studies. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014. 132: p. 604-614.
Kang, D., J. Seo, S.Y. Lee, J.Y. Lee, K.S. Choi, and S.S. Lee, First dicadmium (II) complex of tripodal amide ligand with one edge-sharing monocapped octahedral geometry. Inorganic Chemistry Communications, 2007. 10(12): p. 1425-1428.
Noyori, R. and R. Noyori, Asymmetric catalysis in organic synthesis. 1994.
El-Asmy, A.A., A. Al-Abdeen, W.A. El-Maaty, and M. Mostafa, Synthesis and spectroscopic studies of 2, 5-hexanedione bis (isonicotinylhydrazone) and its first raw transition metal complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2010. 75(5): p. 1516-1522.
Lee, R.F., S. Theiner, A. Meibom, G. Koellensperger, B.K. Keppler, and P.J. Dyson, Application of imaging mass spectrometry approaches to facilitate metal-based anticancer drug research. Metallomics, 2017. 9(4): p. 365-381.
El-Boraey, H.A. and A.I. Mansour, Synthesis, spectral and gamma ray irradiation studies on metal complexes of N, N'-naphthalene-1, 8-diylbis (2-aminobenzamide). Inorganic and Nano-Metal Chemistry, 2017(just-accepted): p. 00-00.
Raman, N., Y.P. Raja, and A. Kulandaisamy. Synthesis and characterization of Cu (II), Ni (II), Mn (II), Zn (II) and VO (II) Schiff base complexes derived from o-phenylenediamine and acetoacetanilide. in PROCEEDINGS-INDIAN ACADEMY OF SCIENCES CHEMICAL SCIENCES. 2001. Indian Academy of Sciences; 1999.
Tyagi, P., M. Tyagi, S. Agrawal, S. Chandra, H. Ojha, and M. Pathak, Synthesis, characterization of 1, 2, 4-triazole Schiff base derived 3d-metal complexes: Induces cytotoxicity in HepG2, MCF-7 cell line, BSA binding fluorescence and DFT study. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2017. 171: p. 246-257.
Bassett, J., J. Bassett, R. Denney, G. Jeffery, and J. Mentham, Vogel's Textbook of Quantitative Inorganic Analysis: Including Elementry Instrumental Analysis. 1985: Longman ELBS.
West, T.S., Complexometry with EDTA and related reagents. 1969: BDH Chemicals Ltd.
Swamy, S., K. Suresh, P. Someshwar, and D. Nagaraju, Synthesis of novel Schiff's bases containing pyridine rings. Synthetic communications, 2004. 34(10): p. 1847-1853.
Bauer, A., W. Kirby, J.C. Sherris, and M. Turck, Antibiotic susceptibility testing by a standardized single disk method. American journal of clinical pathology, 1966. 45(4): p. 493.
PANKUCH, G.A., M.R. JACOBS, and P.C. APPELBAUM, Activity of CP 99, 219 compared with DU-6859a, ciprofloxacin, ofloxacin, levofloxacin, lomefloxacin, tosufloxacin, sparfloxacin and grepaloxacin against penicillin-susceptible and-resistant pneumococci. Journal of Antimicrobial Chemotherapy, 1995. 35(1): p. 230-232.
Ostrosky-Zeichner, L., J.H. Rex, M.A. Pfaller, D.J. Diekema, B.D. Alexander, D. Andes, S.D. Brown, V. Chaturvedi, M.A. Ghannoum, and C.C. Knapp, Rationale for reading fluconazole MICs at 24 hours rather than 48 hours when testing Candida spp. by the CLSI M27-A2 standard method. Antimicrobial agents and chemotherapy, 2008. 52(11): p. 4175-4177.
Yousif, E., A. Majeed, K. Al-Sammarrae, N. Salih, J. Salimon, and B. Abdullah, Metal complexes of Schiff base: preparation, characterization and antibacterial activity. Arabian Journal of Chemistry, 2017. 10: p. S1639-S1644.
Dhayabaran, V.V. and T.D. Prakash, Spectral And Theoretical Studies On The Impact Of M (II) Complexes Of Amino Acid-Nucleobase Hybrid Ligand On BSA Binding: An Approach Towards New Metallodrugs. 2017.
Gull, P., S.A. AL-Thabaiti, and A.A. Hashmi, Design, Characterization and antimicrobial activity of Cu (II), Co (II) and Zn (II) complexes with Schiff base from 1, 2-diphenylethane-1, 2-dione and N-(1-Naphthyl) ethylenediamine. Int. J. of Multidisciplinary and Current research, 2014.
Swamy, S., B. Veerapratap, D. Nagaraju, K. Suresh, and P. Someshwar, Non-template synthesis of ‘N4’di-and tetra-amide macrocylic ligands with variable ring sizes. Tetrahedron, 2003. 59(50): p. 10093-10096.
El-Boraey, H.A. and A.A.S. El-Din, Transition metal complexes of a new 15-membered [N5] penta-azamacrocyclic ligand with their spectral and anticancer studies. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014. 132: p. 663-671.
El-Boraey, H.A. and O.A. El-Gammal, New 15-membered tetraaza (N 4) macrocyclic ligand and its transition metal complexes: spectral, magnetic, thermal and anticancer activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2015. 138: p. 553-562.
Ayad, M.I. and H.A. El-Boraey, Characterization, thermal and electrical conductivity of some transition metal adducts. International Journal of ChemTech Research, 2014. 6(1): p. 266-275.
El-Boraey, H.A., S.M. Emam, D.A. Tolan, and A.M. El-Nahas, Structural studies and anticancer activity of a novel (N6O4) macrocyclic ligand and its Cu (II) complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2011. 78(1): p. 360-370.
Chaudhary, A. and R. Singh, Txicological Aspects of Newly Designed Macrocyclic Complexes of Iron (II). Metal-based drugs, 2002. 8(6): p. 315-321.
Angelusiu, M.V., G.L. Almajan, T. Rosu, M. Negoiu, E.-R. Almajan, and J. Roy, Copper (II) and uranyl (II) complexes with acylthiosemicarbazide: Synthesis, characterization, antibacterial activity and effects on the growth of promyelocytic leukemia cells HL-60. European journal of medicinal chemistry, 2009. 44(8): p. 3323-3329.
Joseyphus, R.S. and M.S. Nair, Synthesis, characterization and biological studies of some Co (II), Ni (II) and Cu (II) complexes derived from indole-3-carboxaldehyde and glycylglycine as Schiff base ligand. Arabian Journal of Chemistry, 2010. 3(4): p. 195-204.
Abd El?Halim, H., G.G. Mohamed, and M.N. Anwar, Antimicrobial and anticancer activities of Schiff base ligand and its transition metal mixed ligand complexes with heterocyclic base. Applied Organometallic Chemistry, 2018. 32(1).
Chandra, S. and U. Kumar, Spectral and magnetic studies on manganese (II), cobalt (II) and nickel (II) complexes with Schiff bases. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2005. 61(1-2): p. 219-224.
Shakir, M., A. Abbasi, M. Azam, and A.U. Khan, Synthesis, spectroscopic studies and crystal structure of the Schiff base ligand L derived from condensation of 2-thiophenecarboxaldehyde and 3, 3?-diaminobenzidine and its complexes with Co (II), Ni (II), Cu (II), Cd (II) and Hg (II): Comparative DNA binding studies of L and its Co (II), Ni (II) and Cu (II) complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2011. 79(5): p. 1866-1875.
Omar, M. and G.G. Mohamed, Potentiometric, spectroscopic and thermal studies on the metal chelates of 1-(2-thiazolylazo)-2-naphthalenol. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2005. 61(5): p. 929-936.
Jayashri, T. and K. Viji, Spectral, X-ray diffraction, surface morphological and thermal studies of gamma-irradiated potassium bis (oxalato) zincate (II) dihydrate. Radiation Effects and Defects in Solids, 2018: p. 1-10.
Shebl, M., Synthesis, spectroscopic characterization and antimicrobial activity of binuclear metal complexes of a new asymmetrical Schiff base ligand: DNA binding affinity of copper (II) complexes. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2014. 117: p. 127-137.
Hatakeyama, T. and Z. Liu, Thermal analysis curves of minerals. Handbook of thermal analysis. Chichester, England: Wiley, 1998: p. 247-336.
Al-Shihri, A.S., Synthesis, characterization and thermal analysis of some new transition metal complexes of a polydentate Schiff base. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2004. 60(5): p. 1189-1192.
Gayathri, N. and M. Suresh, Synthesis and spectral characterization of oxovanadium complexes derived from benzoin, O-phenylenediamine and ethylenediamine and their antibacterial activities. Int. J. Curr. Res. Chem. Pharm. Sci, 2017. 4(1): p. 12-19.
Abdel?Rahman, L.H., A.M. Abu?Dief, H. Moustafa, and S.K. Hamdan, Ni (II) and Cu (II) complexes with ONNO asymmetric tetradentate Schiff base ligand: synthesis, spectroscopic characterization, theoretical calculations, DNA interaction and antimicrobial studies. Applied Organometallic Chemistry, 2017. 31(2).
El-Boraey, H.A. and M.A. El-Salamony, Transition Metal Complexes with Polydentate Ligand: Synthesis, Characterization, 3D Molecular Modelling, Anticancer, Antioxidant and Antibacterial Evaluation. Journal of Inorganic and Organometallic Polymers and Materials, 2019. 29(3): p. 684-700.
Masoud, M.S., S.S. Hagagg, A.E. Ali, and N.M. Nasr, Synthesis and spectroscopic characterization of gallic acid and some of its azo complexes. Journal of Molecular Structure, 2012. 1014: p. 17-25.
Copyright (c) 2019 Hanaa A. El-Boraey, Azza A. Serag El-Din, Ahmed A. Sakr
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors retain the copyright of their manuscripts, and all Open Access articles are distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided that the original work is properly cited.