Synthesis, Spectral Characterization, Thermal and In vitro Antimicrobial Studies for Novel Co(II) and Ni(II) Complexes of (N,N'-(1,2-Phenylene)Bis(2-Aminobenzamide).

  • Hanaa A. El-Boraey Menoufia University
  • Azza A. Serag El-Din The Regional Institute Joint of Medical and Chemical Analysis
  • Ahmed A. Sakr Menoufia University
Keywords: Synthesis, Spectral, Thermal Studies, Metal Complexes, Antibacterial, Antifungal Activity

Abstract

Novel metal complexes of Co(II) and Ni(II) have been  prepared from reaction of their different salts with previously prepared ligand (L) namely (N,N'-(1,2-phenylene)bis(2-aminobenzamide). Synthesis ligand and its metal (II) complexes (1-5) were reported and characterized with the help of analytical and physiochemical analysis as elemental, IR spectra, thermal (TG/DTG), UV-Vis, magnetic susceptibility and molar conductance in DMF, On the view of the previous data and measurements, the structure and composition species behave as mononuclear and octahedral geometry has been proposed for all the complexes except for complex (1) adopted tetrahedral structure. Furthermore, the in vitro antibacterial Staphylococcus aureus (ATCC 25923) as Gram-positive strain, Escherichia coli (ATCC 25922) as Gram-negative strain and antifungal Candida albicans (ATCC 10231) have been studied for all samples using disc diffusion method against Ampicillin and Fluconazole as positive controls, respectively. The results show that complexation facilitates the activity of most studied metal complexes than the free ligand.

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Author Biographies

Hanaa A. El-Boraey, Menoufia University

Department of Chemistry, Faculty of Science, Menoufia University, Shebin El- Kom, Egypt

Azza A. Serag El-Din, The Regional Institute Joint of Medical and Chemical Analysis

Department of Chemistry, The Regional Institute Joint of Medical and Chemical  Analysis,  Ministry of Health, Shebin El-Kom, Egypt

Ahmed A. Sakr, Menoufia University

Department of Chemistry, Faculty of Science, Menoufia University, Shebin El- Kom, Egypt.

 

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Published
2019-04-30
How to Cite
A. El-Boraey, H., Serag El-Din, A. A., & Sakr, A. A. (2019). Synthesis, Spectral Characterization, Thermal and In vitro Antimicrobial Studies for Novel Co(II) and Ni(II) Complexes of (N,N’-(1,2-Phenylene)Bis(2-Aminobenzamide). JOURNAL OF ADVANCES IN CHEMISTRY, 16, 5360-5374. https://doi.org/10.24297/jac.v16i0.8264
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Articles