Management and Risk in the Frame of Ipm with Biological Control Methods

  • Marian Lixandru Res Institute for Plant Protection, Bucharest , Romania
  • Sergiu Fendrihan Res Institute for Plant Protection-Ion Ionescu de la Brad nr 8, Bucharest , Romania
Keywords: IPM, plant protection, biocontrol, eco agriculture, agriculture


The demographic development of human population, the pollution, with pesticides, the needs for better quality crops, determined the farmers, policy makers, scientists and the public to make steps further in order to adopt strategies, to issue laws, guides, directives to implement in practice the use of IPM and biological control of pests and Phyto-pathogens for implementing sano-genetic advanced agriculture. This is a short review paper discussing the modern and future IPM.


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Author Biography

Marian Lixandru, Res Institute for Plant Protection, Bucharest , Romania

Res Institute for Plant Protection-Ion Ionescu de la Brad nr 8, Bucharest , Romania


Aznar-Fernández T, Cimmino A, Masi M, Rubiales D, Evidente A. (2018) Antifeedant activity of long-chain alcohols, and fungal and plant metabolites against pea aphid (Acyrthosiphon pisum) as potential biocontrol strategy.Nat Prod Res. 2018 Mar 29:1-9.

Álvarez B, Biosca EG.Bacteriophage-Based Bacterial Wilt Biocontrol for an Environmentally Sustainable Agriculture.Front Plant Sci. 2017;8:12-18.

Baker S, Volova T, Prudnikova SV, Satish S, Prasad M N N (2017) Nanoagroparticles emerging trends and future prospect in modern agriculture system.Environ Toxicol Pharmacol.;53:10-17.

Barilli E, Cimmino A, Masi M, Evidente M, Rubiales D, Evidente A. (2017) Inhibition of early development stages of rust fungi by the two fungal metabolites cyclopaldic acid and epi-epoformin.Pest Manag Sci. 2017 Jun;73(6):1161-1168. doi: 10.1002/ps.4438. Epub 2016 Nov 16.

Biondi A, Desneux N, Siscaro G, Zappalà L. (2012) Using organic-certified rather than synthetic pesticides may not be safer for biological control agents: selectivity and side effects of 14 pesticides on the predator Orius laevigatus.Chemosphere.;87 (7):803-12.

Bradberry SM, Cage SA, Proudfoot AT, Vale JA. (2005) Poisoning due to pyrethroids. Toxicol Rev. 2005; 24 (2):93-106.

Benelli G, Pavela R, Lupidi G, Nabissi M, Petrelli R, Ngahang Kamte SL, Cappellacci L, Fiorini D, Sut S, Dall'Acqua S, Maggi F (2018) The crop-residue of fiber hemp cv. Futura 75: from a waste product to a source of botanical insecticides.Environ Sci Pollut Res Int. 2018 Apr;25(11):10515-10525.

Benelli G, Pavela R, Canale A, Cianfaglione K, Ciaschetti G, Conti F, Nicoletti M, Senthil-Nathan S, Mehlhorn H, Maggi F. (2017) Acute larvicidal toxicity of five essential oils (Pinus nigra, Hyssopus officinalis, Satureja montana, Aloysia citrodora and Pelargonium graveolens) against the filariasis vector Culex quinquefasciatus: Synergistic and antagonistic effects.Parasitol Int.; 66 (2):166-171.

Benelli G, Canale A, Toniolo C, Higuchi A, Murugan K, Pavela R, Nicoletti M. (2016) Neem (Azadirachta indica): towards the ideal insecticide?Nat Prod Res.;31(4):369-386.

Biddinger DJ, Leslie TW, Joshi NK. (2014) Reduced-risk pest management programs for eastern U.S. peach orchards: effects on arthropod predators, parasitoids, and select pests.J Econ Entomol. 2014 Jun;107(3):1084-91.

Bonmatin JM, Giorio C, Girolami V, Goulson D, Kreutzweiser DP, Krupke C, Liess M, Long E, Marzaro M, Mitchell EA, Noome DA, Simon-Delso N, Tapparo A. Environmental fate and exposure; neonicotinoids and fipronil. Environ Sci Pollut Res Int. 2015 Jan;22(1):35-67.

Céspedes CL, Salazar JR, Ariza-Castolo A, Yamaguchi L, Avila JG, Aqueveque P, Kubo I, Alarcón JBiopesticides from plants: Calceolaria integrifolia s.l.Environ Res. 2014 Jul;132:391-406.

Chandler D, Alastair S. Bailey, G. Mark Tatchell,Gill Davidson, Justin Greaves, Wyn P. Grant (2011) The development, regulation and use of biopesticides for integrated pest management. Phil. Trans. R. Soc. B (2011) 366, 1987–1998.

Crouse GD, Demeter DA, Samaritoni G, McLeod CL, Sparks TC. 2018De Novo Design of Potent, Insecticidal Synthetic Mimics of the Spinosyn Macrolide Natural Products.Sci Rep.;8(1):4861. doi: 10.1038/s41598-018-22894-6.

Codling G, Naggar YA, Giesy JP, Robertson AJ. (2018) Neonicotinoid insecticides in pollen, honey and adult bees in colonies of the European honey bee (Apis mellifera L.) in Egypt.Ecotoxicology. ;27(2):122-131.

Chagnon M, Kreutzweiser D, Mitchell EA, Morrissey CA, Noome DA, Van der Sluijs JP. (2015) Risks of large-scale use of systemic insecticides to ecosystem functioning and services.Environ Sci Pollut Res Int.;22(1):119-34.

Czaja K., Góralczyk K., Struci?ski P., Hernik A., Korcz W., Minorczyk M., ?yczewska M., Ludwicki JK (2018) Biopesticides – towards increased consumer safety in the EU (accepted but not publish yet)

Dukare AS, Paul S, Nambi VE, Gupta RK, Singh R, Sharma K, Vishwakarma RK. Exploitation of microbial antagonists for the control of postharvest diseases of fruits: a review’s 2018 Jan 16:1-16.

Ebadollahi A, Sendi J.J., Maroufpoor M., Rahimi-Nasrabadi M.(2017) Acaricidal Potentials of the Terpene-rich EssentialOils of Two Iranian Eucalyptus Species againstTetranychus urticae KochJ. Oleo Sci. 66, (3) 307-314.

Fang W, Azimzadeh P, St Leger RJ. (2012) Strain improvement of fungal insecticides for controlling insect pests and vector-borne diseases.Curr Opin Microbiol.;15(3):232-8.

Furlan L, Pozzebon A, Duso C, Simon-Delso N, Sánchez-Bayo F, Marchand PA, Codato F, Bijleveld van Lexmond M, Bonmatin JM (2018) An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 3: alternatives to systemic insecticides. Environ Sci Pollut Res Int. 2018 Feb 25. doi: 10.1007/s11356-017-1052-5.

Giorio C, Safer A, Sánchez-Bayo F, Tapparo A, Lentola A, Girolami V, van Lexmond MB, Bonmatin JM (2017) An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 1: new molecules, metabolism, fate, and transport.Environ Sci Pollut ResInt. 2017 Nov 5. doi: 10.1007/s11356-017-0394-3.

Golden G, Quinn E, Shaaya E, Kostyukovsky M, Poverenov E(2018) Coarse and nano emulsions for effective delivery of the natural pest control agent pulegone for stored grain protection.Pest Manag Sci. 2018 Apr;74(4):820-827.

Hall RG, Bruce I, Cooke NG, Diorazio LJ, Cederbaum F, Dobler MR, Irving E(2017)Investigating the Structure-Activity Relationship of the Insecticidal Natural Product Rocaglamide.Chimia (Aarau).;71(12):845-850.

Han JW, Shim SH, Jang KS, Choi YH, Dang QL, Kim H, Choi GJ(2018) In vivo assessment of plant extracts for control of plant diseases: A sesquiterpene ketolactone isolated from Curcuma zedoaria suppresses wheat leaf rust.J Environ Sci Health B. ;53(2):135-140

Hwang KS, Kim YK, Park KW, Kim YT. (2017)Piperolein B and piperchabamide D isolated from black pepper (Piper nigrum L.) as larvicidal compounds against the diamondback moth (Plutella xylostella).Pest Manag Sci.;73(8):1564-1567.

Jang M, Kim J, Yoon KA Lee SH, Park CG (2017) Biological activity of Myrtaceae plant essential oils and their major components against Drosophila suzukii (Diptera: Drosophilidae). Pest Manag Sci. ;73(2):404-409.

Ji X, Wang Z, Dong J, Liu Y, Lu A, Wang Q (2016) Discovery of Topsentin Alkaloids and Their Derivatives as Novel Antiviral and Anti-phytopathogenic Fungus Agents.J. Agric Food Chem.;64(48):9143-9151.

Khandelwal N, Barbole RS, Banerjee SS, Chate GP, Biradar AV, Khandare JJ, Giri AP. (2016)Budding trends in integrated pest management using advanced micro- and nano-materials: Challenges and perspectives.J Environ Manage.;184(Pt 2):157-169

Kirst HAThe spinosyn family of insecticides: realizing the potential of natural products research.J Antibiot (Tokyo). 2010 Mar;63(3):101-11.

Kumar S, Chandra A, Pandey KC. (2008) Bacillus thuringiensis (Bt) transgenic crop: an environment friendly insect-pest management strategy.J Environ Biol.;29(5):641-53.

Ibrahim S, Mohamed GA, Al Haidari RA, El-Kholy AA, Zayed MF. (2018) Potential Anti-Malarial Agents from Endophytic Fungi: A Review.Mini Rev Med Chem. 2018 Mar 5. doi: 10.2174/1389557518666180305163151.

Loiseleur O (2017) Natural Products in the Discovery of Agrochemicals.Chimia (Aarau);71(12):810-822.

La Torre A, Talocci S, Spera G, Valori R. (2008) Control of downy mildew on grapes in organic viticulture.Commun Agric Appl Biol Sci. ;73 (2):169-78.

Mahnaz K, Alireza F, Vatandoost H., Mahdi S., Reza A.M.,Abbas H. (2012) Larvicidal activity of essential oil and methanol extract of Nepeta menthoidesagainst malaria vector Anopheles stephensiAsian Pacific Journal of Tropical Medicine (2012)962-965.

Matyjaszczyk E. (2017) Plant protection means used in organic farming throughout theEuropean Union. Pest Management Science DOI: 10.1002/ps.4789

Marchand PA, Dimier-Vallet C, Vidal R (2017) Biorational substitution of piperonyl butoxide in organic production: effectiveness of vegetable oils as synergists for pyrethrums.Environ Sci Pollut Res Int. 2017 Dec 22. doi: 10.1007/s11356-017-1057-0.

Mall D., Larsen A.E., Martin EA. (2018) Investigating the (Mis)Match between Natural Pest Control Knowledge and the Intensity of Pesticide Use Insects.; 9(1): 2.doi: 10.3390/insects9010002PMCID: PMC5872267

Morgunov IG, Kamzolova SV, Dedyukhina EG, Chistyakova TI, Lunina JN, Mironov AA, Stepanova NN, Shemshura ON, Vainshtein MB (2017) Application of organic acids for plant protection against phytopathogens.Appl Microbiol Biotechnol. ;101(3):921-932.

Morán-Diez ME, Glare TR. (2016) What are Microbial-based Biopesticides?Methods Mol Biol.;1477:1-10.

Nisa H, Kamili AN, Nawchoo IA, Shafi S, Shameem N, Bandh SA. (2015) Fungal endophytes as prolific source of phytochemicals and other bioactive natural products: A review.Microb Pathog.;82:50-9.

Nikkhah M, Hashemi M, Habibi Najafi MB, Farhoosh R (2017) Synergistic effects of some essential oils against fungal spoilage on pear fruit.Int J Food Microbiol.;257:285-294.

Neeraja C, Anil K, Purushotham P, Suma K, Sarma P, Moerschbacher BM, Podile AR. (2010) Biotechnological approaches to develop bacterial chitinases as a bioshield against fungal diseases of Rev Biotechnol.;30(3):231-41.

Pavela R. (2018) Essential oils from Foeniculum vulgare Miller as a safe environmental insecticide against the aphid Myzus persicae Sulzer.Environ Sci Pollut Res Int. 2018 Apr;25(11):10904-10910.

Pisa L, Goulson D, Yang EC, Gibbons D, Sánchez-Bayo F, Mitchell E, Aebi A, van der Sluijs J, MacQuarrie CJK, Giorio C, Long EY, McField M, Bijleveld van Lexmond M, Bonmatin JM(2017) An update of the Worldwide Integrated Assessment (WIA) on systemic insecticides. Part 2: impacts on organisms and ecosystems.Environ Sci Pollut Res Int. 2017 Nov 9. doi: 10.1007/s11356-017-0341-3.

Peterson JA, Ode PJ, Oliveira-Hofman C, Harwood JD. (2016) Integration of Plant Defense Traits with Biological Control of Arthropod Pests: Challenges and Opportunities. Front Plant Sci.;7:1794. eCollection 2016.

Radwan MM, Tabanca N, Wedge DE, Tarawneh AH, Cutler SJ. (2014) Antifungal compounds from turmeric and nutmeg with activity against plant pathogens.Fitoterapia.;99:341-6.

Razinger J, Vasileiadis VP, Giraud M, van Dijk W, Modic Š, Sattin M, Urek G (2016) On-farm evaluation of inundative biological control of Ostrinia nubilalis (Lepidoptera: Crambidae) by Trichogramma brassicae (Hymenoptera: Trichogrammatidae) in three European maize-producing regions. Pest Manag Sci.;72(2):246-54.

Roy S, Handique G, Muraleedharan N, Dashora K, Roy SM, Mukhopadhyay A, Babu A.(2016) Use of plant extracts for tea pest management in India.Appl Microbiol Biotechnol. ;100 (11):4831-44.

Santamarina MP, Ibáñez M.D., Marqués M, Roselló J, Giménez S, Blázquez MA (2017) Bioactivity of essential oils in phytopathogenic and post-harvest fungi control, Natural Product Research, 31:22, 2675-2679.Seiber JN, Coats J, Duke SO, Gross AD. (2014) Biopesticides: state of the art and future opportunities.J Agric Food Chem.;62 (48):11613-9.

Shakeel M, Farooq M, Nasim W, Akram W, Khan FZA, Jaleel W, Zhu X, Yin H, Li S, Fahad S, Hussain S, Chauhan BS Jin F (2017) Environment polluting conventional chemical control compared to an environmentally friendly IPM approach for control of diamondback moth, Plutella xylostella (L.), in China: a review. Environ Sci Pollut Res Int.;24(17):14537-14550.

Song PP, Zhao J, Liu ZL, Duan YB, Hou YP, Zhao CQ, Wu M, Wei M, Wang NH, Lv Y, Han ZJ. (2017) Evaluation of antifungal activities and structure-activity relationships of coumarin derivatives.Pest Manag Sci.;73(1):94-101.

Sparks TC, Hahn DR, Garizi NV (2017) Natural products, their derivatives, mimics and synthetic equivalents: role in agrochemical discovery.Pest Manag Sci.;73(4):700-715.

Sparks TC, Lorsbach BA (2016) Perspectives on the agrochemical industry and agrochemical discovery Published online in Wiley Online Library: 16 December 2016 ( DOI 10.1002/ps.4457

Swiontek-Brzezinska M., Jankiewicz U., Burkowska A., Walczak M. (2014) Chitinolytic Microorganisms and Their Possible Application in Environmental Protection Curr Microbiol 68:71–81

Tomasetto F, Tylianakis JM, Reale M, Wratten S, Goldson SL (2017) Intensified agriculture favors evolved resistance to biological control.Proc Natl Acad Sci U S A. ;114(15):3885-3890.

Villaverde JJ, Sevilla-Morán B, Sandín-España P, López-Goti C, Alonso-Prados JL. (2014) Biopesticides in the framework of the European Pesticide Regulation (EC) No. 1107/2009.Pest Manag Sci.;70(1):2-5.

Vinale F, Nicoletti R, Lacatena F, Marra R, Sacco A, Lombardi N, d'Errico G, Digilio MC, Lorito M, Woo SL (2017) Secondary metabolites from the endophytic fungus Talaromyces pinophilus.Nat Prod Res. 2017 Aug;31(15):1778-1785.

Wei C, Liu J, Maina AN, Mwaura FB, Yu J, Yan C, Zhang R, Wei H. (2017) Developing a bacteriophage cocktail for biocontrol of potato bacterial wilt.Virol Sin. ;32(6):476-484.

Xia Q, Dong J, Li L, Wang Q, Liu Y, Wang Q (2018) Discovery of Glycosylated Genipin Derivatives as Novel Antiviral, Insecticidal, and Fungicidal Agents.J Agric Food Chem.;66(6):1341-1348.

Zhao H, Lovett B, Fang W. (2016) Genetically Engineering Entomopathogenic Fungi.Adv Genet. 2016;94:137-63.

ZhaoX., Haixin Cui, Yan Wang, Changjiao Sun, Bo Cui, and Zhanghua Zeng (2017) Development strategies and prospects of nano-based smart pesticide formulation J. Agric. Food Chem., Just Accepted Manuscript DOI: 10.1021/acs.jafc.7b02004 Publication Date (Web): 27 Jun 2017.

How to Cite
Lixandru, M., & Fendrihan, S. (2018). Management and Risk in the Frame of Ipm with Biological Control Methods. JOURNAL OF ADVANCES IN AGRICULTURE, 8(1), 1488-1497.

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